A comparative study of insulin levels in lean versus obese polycystic ovarian syndrome patients
نویسندگان
چکیده
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women reproductive age group. PCOS has been frequently associated with insulin resistance and obesity. Although cases are obese or overweight, a significant proportion patients have normal body mass index (BMI≤25 kg/m2) that makes diagnostic work up therapeutic approach more difficult. These referred to as “lean PCOS.” Methods: This hospital based prospective, comparative cross-sectional study was conducted estimate levels lean versus over-weight evaluate correlation BMI clinical parameters, serum levels, hormone profile these patients. Patients were grouped according their BMI: Lean group-(n=46) BMI<25 kg/m2 group-(n=40) BMI≥25 kg/m2. Results: Serum significantly higher than (p<0.001). Overweight achieved HOMA-IR The difference fasting blood sugar not different. Comparisons two groups showed no statistical differences gonadotrophins (LH FSH) values LH/FSH ratio. testosterone level group compared (p=0.043). Conclusions: We conclude overweight/obese had tendency develop elevated counterparts. Thus, weight reduction metformin therapy hold great potential managing patient but will much effect on hormonal PCOS.
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ژورنال
عنوان ژورنال: International journal of reproduction, contraception, obstetrics and gynecology
سال: 2023
ISSN: ['2320-1770', '2320-1789']
DOI: https://doi.org/10.18203/2320-1770.ijrcog20230783